Skip to Navigation Skip to Search Skip to Content
Search All Centers

Is Acute Lymphoblastic Leukemia the Same in Every Patient?

Read Transcript Download/Print Transcript

Published on January 7, 2020

Key Takeaways

How does acute lymphoblastic leukemia differ from patient to patient? Noted expert Dr. Ryan Cassaday from the University of Washington School of Medicine discusses the two different lineages of ALL, some key genetic distinctions and how this impacts prognosis and treatment. Watch now to learn more from an ALL expert. 

 

Featuring

Your site is AWESOME! Thank you all so much for this incredible resource to families who are in crisis/affected by cancer.

— Loyal Patient Power viewer

You might also like

Transcript | Is Acute Lymphoblastic Leukemia the Same in Every Patient?

And then going even deeper into the sort of genomic and genetic level there are—another key distinction is the Philadelphia chromosome, the BCR‑ABL translocation, which is more commonly associated with CML but is also really important in ALL.  But depending on the age range anywhere from 5 to 50 percent of patients with ALL will have that genetic abnormality.  That's really important in terms of deciding treatment and prognosis. 

Up until maybe five‑ish, 10 years ago maybe that was kind of the key distinction really in terms of making treatment decisions, but it's gotten a lot more sophisticated recently with increased understanding of other genetic pathways that are important that might predict response to treatment, might confer a certain prognosis. 

And you're absolutely right.  Genes that we talk about in this disease are not genes that you inherited in a defective manner from your parents or that you could pass along to your children.  These are genes that get mutated or become abnormal in the context of developing the ALL, so they're very specific and unique to the malignant cells. 

Please remember the opinions expressed on Patient Power are not necessarily the views of our sponsors, contributors, partners or Patient Power. Our discussions are not a substitute for seeking medical advice or care from your own doctor. That’s how you’ll get care that’s most appropriate for you.

Recommended for You

You might also like