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Which Are the Main Breast Cancer Subtypes?

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Published on September 24, 2017

Breast cancer is not one single disease anymore, but what are the four subtypes of breast cancer? Dr. Giuseppe Curigliano from Istituto Europeo di Oncologia (Milan, Italy) explains the breast cancer subtypes and which treatments are best for each type. 

This interview was recorded at the European Society of Medical Oncology (ESMO) congress held in Madrid (September 2017). Breast cancer videos recorded at ESMO 17 are part of an educational program by the Patient Empowerment Foundation (PEF). We thank Roche for their support.

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Transcript |

Please remember the opinions expressed on Patient Power are not necessarily the views of our sponsors, contributors, partners or Patient Power. Our discussions are not a substitute for seeking medical advice or care from your own doctor. That's how you’ll get care that's most appropriate for you.

Please remember the opinions expressed on Patient Power are not necessarily the views of our sponsors, contributors, partners or Patient Power. Our discussions are not a substitute for seeking medical advice or care from your own doctor. That’s how you’ll get care that’s most appropriate for you.

Dr. Curigliano:

We have at least four breast cancer subtypes. The first one is basal-like. It is more aggressive in terms of evolution and a poor prognosis. But at the same time if early diagnosis that you do with the very best of care, it can be cured. Then we have the HER2-positive that is a subtype that is responsive through therapy with pertuzumab (Perjeta) and trastuzumab (Herceptin). 

And then we have the luminal A and the luminal B. The luminal A is a very good prognosis cancer with a high expression of estrogen-receptor, progesterone-receptor. And the luminal B is quite similar to luminal A but with higher proliferating index. That’s why for the luminal B you need to treat much more, so you need a hormone therapy plus chemotherapy.

Please remember the opinions expressed on Patient Power are not necessarily the views of our sponsors, contributors, partners or Patient Power. Our discussions are not a substitute for seeking medical advice or care from your own doctor. That’s how you’ll get care that’s most appropriate for you.