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Should CLL Patients Undergo Genetic Testing?

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Published on August 21, 2015

Should CLL patients undergo genetic testing? Dr. Nitin Jain, a CLL expert from MD Anderson Cancer Center, discusses comprehensive genomic testing resources for patients.Dr. Jain shares his opinion on genetic testing schedules and timing in order to yield optimal information about each patient’s individual CLL. 

Sponsored by the Patient Empowerment Network, which received educational grants from AbbVie and Genentech. 

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Transcript | Should CLL Patients Undergo Genetic Testing?

Please remember the opinions expressed on Patient Power are not necessarily the views of our sponsors, contributors, partners or Patient Power. Our discussions are not a substitute for seeking medical advice or care from your own doctor. That's how you’ll get care that's most appropriate for you.

Please remember the opinions expressed on Patient Power are not necessarily the views of our sponsors, contributors, partners or Patient Power. Our discussions are not a substitute for seeking medical advice or care from your own doctor. That’s how you’ll get care that’s most appropriate for you. 

Carol Preston:

We do. We have a question from Cheryl. And she would like to know would it be helpful to have her DNA genomic profile taken to learn what her particular CLL is and how to deal with it?

Dr. Jain:                 

So it’s very essential that once you’re diagnosed with CLL, you go to a center where you have the resources and capabilities to do all of the genomic testing.  So I think there are some things which are I think becoming standards.  Like CLL FISH panel, mutation status, ZAP-70 we talked about, CV38 expression, CD49D. So those are things, which are, I think becoming more and more standard across the board at major medical centers.

And I think your doctor should be testing for those things.  Besides that, there are a lot of research aspects to it.  There are several other mutations, abnormalities in the genetic DNA, which have been described, which are being done majority as part of research trials right now or research sample collection, which I think I would encourage you to be a part of it.  But certainly, to the online person, I would say that you should get that testing done and, again, standard as for most major medical centers in the country.                  

Please remember the opinions expressed on Patient Power are not necessarily the views of our sponsors, contributors, partners or Patient Power. Our discussions are not a substitute for seeking medical advice or care from your own doctor. That’s how you’ll get care that’s most appropriate for you. 

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