Skip to Navigation Skip to Search Skip to Content
Search All Centers

Drugs Used for Myeloma are Helping Fight COVID-19

Read Transcript
View next

Published on July 16, 2020

Several anti-inflammatory drugs used to treat multiple myeloma are showing promising results treating Covid-19.
 
Dr. James Berenson cautions that anti-inflammatory drugs like dexamethasone, medrol, and prednisone should not be considered for early treatment of Covid-19, but are showing positive results on Covid-19 patients in later stages.
 
In addition, there is research being done on the use of ruxolitinib and selinexor in treating Covid-19. There is also anecdotal evidence that myeloma patients who are already in treatment are recovering well from Covid-19 while on these drugs.
  

Featuring

Transcript | Drugs Used for Myeloma are Helping Fight COVID-19

Please remember the opinions expressed on Patient Power are not necessarily the views of our sponsors, contributors, partners or Patient Power. Our discussions are not a substitute for seeking medical advice or care from your own doctor. That’s how you’ll get care that’s most appropriate for you.

Andrew Schorr:

Dr. Berenson there's data that came out of the UK. They were very excited there about the use of dexamethasone (Decadron), which is widely used in myeloma to help some of the sickest patients with complications of COVID-19. US doctors were waiting for data and maybe there are other tools as well. Your comment on that.

Dr. Berenson:

Yeah. I think this is good news, but I think the news is really, it's an anti-inflammatory, it reduces the inflammation. It really shouldn't in my view, be used early in the infection with coronavirus, but late when you start getting the pulmonary symptoms of shortness of breath from all the inflammation in the lung. And I have seen that effective in my own patients who've had coronavirus as well as believe it or not a staff member with immediate intervention have a dramatic reversal with steroids. It doesn't necessarily have to be dexamethasone, it could be methylprednisolone, otherwise known as Medrol, which I've used a lot or Prednisone, but I think that can help. And in that regard, there are studies being done with other myeloma drugs that are anti-inflammatory. The anti-L6 antibodies have been used somewhat successfully. There's a report published out of China.

And then also recently there are studies with a drug we're doing a ton of work that you're very familiar with. Ruxolitinib (Jakafi) is being used in a randomized study to see if it can help conquer some of the pulmonary or lung side effects of coronavirus. And there's now studies being done with the drug I just mentioned. The selinexor or Xpovio. That drug looks like it maybe a player in treating coronavirus. And there are anecdotes of it being used for myeloma and people had coronavirus and them getting better. So I think there's potentially a number of myeloma drugs besides steroids that may have a role in treating coronavirus or reducing the side effects that occur from all the inflammation that we see.

Please remember the opinions expressed on Patient Power are not necessarily the views of our sponsors, contributors, partners or Patient Power. Our discussions are not a substitute for seeking medical advice or care from your own doctor. That’s how you’ll get care that’s most appropriate for you.

Recommended for You

View next