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Are Blast Cells the Same As Smudge Cells?

Are Blast Cells the Same As Smudge Cells?
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Published on February 3, 2015

Please remember the opinions expressed on Patient Power are not necessarily the views of our sponsors, contributors, partners or Patient Power. Our discussions are not a substitute for seeking medical advice or care from your own doctor. That’s how you’ll get care that’s most appropriate for you. 

Have a question for the experts? Send them to comments@patientpower.info

Question from Heidi:

Are blast cells the same as smudge cells? I have smudge cells on my blood report!

Dr. Leclair: 
Probably not. Smudge cells are exactly that—cells that were destroyed during the collection or preparing of the blood smear. The only thing we can say with comfort is that they must have been much more fragile than the other cells that survived the collection, etc. process. While blasts are fragile, history as shown us that the cells in acute leukemia do not rupture as easily as those found in CLL. And since CLL is characterized by the absence of blasts (as opposed to acute leukemia), we can be reasonably comfortable thinking that the smudge cells are not blasts. 

Please remember the opinions expressed on Patient Power are not necessarily the views of our sponsors, contributors, partners or Patient Power. Our discussions are not a substitute for seeking medical advice or care from your own doctor. That’s how you’ll get care that’s most appropriate for you. 

Have a question for the experts? Send them to comments@patientpower.info

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